Analysis, assessment, and data management are core tools required for operation research analysts. The April 2011 conference held at the Helenic Military Academy addressed these issues with efforts to collect valuable recommendations for improving analysts’ capabilities to assess and communicate the necessary qualitative data to military leaders. This unique volume is an outgrowth of the April conference and comprises of contributions from the fields of science, mathematics, and the military, bringing Greek research findings to the world. Topics cover a wide variety of mathematical methods used with application to defense and security. Each contribution considers directions and pursuits of scientists that pertain to the military as well as the theoretical background required for methods, algorithms, and techniques used in military applications. The direction of theoretical results in these applications is conveyed and open problems and future areas of focus are highlighted. A foreword will be composed by a member of N.A.T.O. or a ranking member of the armed forces. Topics covered include: applied OR and military applications, signal processing, scattering, scientific computing and applications, combat simulation and statistical modeling, satellite remote sensing, and applied informatics – cryptography and coding. The contents of this volume will be of interest to a diverse audience including military operations research analysts, the military community at large, and practitioners working with mathematical methods and applications to informatics and military science.