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Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput Sequencing


Huge Savings Item! Save 18% on the Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput Sequencing by Cambridge University Press at EMS Linux. Hurry! Limited time offer. Offer valid only while supplies last. High-throughput sequencing has revolutionised the field of biological sequence analysis. Its application has enabled researchers to address important


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High-throughput sequencing has revolutionised the field of biological sequence analysis. Its application has enabled researchers to address important biological questions, often for the first time. This book provides an integrated presentation of the fundamental algorithms and data structures that power modern sequence analysis workflows. The topics covered range from the foundations of biological sequence analysis (alignments and hidden Markov models), to classical index structures (k-mer indexes, suffix arrays and suffix trees), Burrows-Wheeler indexes, graph algorithms and a number of advanced omics applications. The chapters feature numerous examples, algorithm visualisations, exercises and problems, each chosen to reflect the steps of large-scale sequencing projects, including read alignment, variant calling, haplotyping, fragment assembly, alignment-free genome comparison, transcript prediction and analysis of metagenomic samples. Each biological problem is accompanied by precise formulations, providing graduate students and researchers in bioinformatics and computer science with a powerful toolkit for the emerging applications of high-throughput sequencing.

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Manufacturer:Cambridge University Press
Publisher:Cambridge University Press
Studio:Cambridge University Press
EAN:9781107078536
Item Weight:2.11 pounds
Item Size:0.87 x 9.72 x 9.72 inches
Package Weight:2.12 pounds
Package Size:6.69 x 0.94 x 0.94 inches

Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput Sequencing by Cambridge University Press

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Genome-Scale Algorithm Design: Biological Sequence Analysis in the Era of High-Throughput Sequencing

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